Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628083 | 0.82 | CYP19A1 (0.37) | CYP19A1NPC1RAB9ARECQLTSHR | |
| SCHEMBL8598745 | 0.81 | TXNRD1 (0.45) | NPC1KMT2AMEN1TSHRHPGD | |
| SCHEMBL8626897 | 0.81 | PAX8 (0.50) | CYP19A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8596386 | 0.79 | S1PR4 (0.58) | NPC1S1PR4RAB9AKMT2AMEN1 | |
| SCHEMBL8599314 | 0.78 | RECQL (0.51) | KMT2AMEN1RECQLTSHRHPGD | |
| SCHEMBL8716642 | 0.78 | KMT2A (0.51) | CYP19A1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL8634277 | 0.77 | CYP19A1 (0.37) | CYP19A1NPC1RAB9ARECQLTSHR | |
| SCHEMBL8711063 | 0.77 | KMT2A (0.50) | KMT2AMEN1RECQLTSHRGLA | |
| SCHEMBL8713770 | 0.77 | KMT2A (0.50) | KMT2AMEN1RECQLTSHRGLA | |
| SCHEMBL8711803 | 0.77 | KMT2A (0.50) | KMT2AMEN1RECQLTSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |