SCHEMBL8628083

SCHEMBL8628083

CCCCCOS(=O)(=O)c1ccnc([N+](=O)[O-])c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.37
CA2 P00918 11/20 0.36
CA1 P00915 10/20 0.36
CA9 Q16790 9/20 0.36
CA12 O43570 4/20 0.36
CA7 P43166 4/20 0.36
CA14 Q9ULX7 3/20 0.36
CA3 P07451 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36
CA5A P35218 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
RECQL P46063 2/20 0.35
TSHR P16473 2/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GLA P06280 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629459 0.82 CYP19A1 (0.39) CYP19A1CA2CA1CA9CA12
SCHEMBL8625161 0.82 CYP19A1 (0.39) CYP19A1RECQLTSHRMAPTGLA
SCHEMBL8596657 0.82 TXNRD1 (0.43) CYP19A1MAPTGAASMN1; SMN2HPGD
SCHEMBL8601222 0.80 MAPT (0.42) CYP19A1MAPTGAASMN1; SMN2MAPK1
SCHEMBL8596152 0.79 RECQL (0.43) CA2CA1CA9CA12RECQL
SCHEMBL8634277 0.78 CYP19A1 (0.37) CYP19A1CA2CA1CA9CA12
SCHEMBL8628187 0.77 CA12 (0.35) CA2CA1CA9CA12CA7
SCHEMBL8626136 0.77 CYP19A1 (0.38) CYP19A1CA2CA1CA9CA12
SCHEMBL8568477 0.76 KMT2A (0.44) CYP19A1CA2CA1CA9CA12
SCHEMBL8599944 0.74 ALDH1A1 (0.49) TSHRMAPTGAAMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed