Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.51 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SORD | Q00796 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416743 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL8329851 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL8320670 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| Ammonia Solution, Strong SCHEMBL4429607 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| Methane SCHEMBL8625321 | 0.81 | GPR119 (0.54) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL8326977 | 0.80 | PLD1 (0.57) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL13622621 | 0.78 | ALDH1A1 (0.62) | KDM4EALDH1A1HSD17B10GPR119L3MBTL1 | |
| SCHEMBL4764379 | 0.77 | PLD1 (0.53) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL1145748 | 0.77 | PLD1 (0.53) | KDM4EALDH1A1MAPTHSD17B10GPR119 | |
| SCHEMBL26627827 | 0.77 | PLD1 (0.53) | KDM4EALDH1A1MAPTHSD17B10GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801173-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-09-01 | — | — | US | disclosed |