Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963709 | 0.78 | KMT2A (0.48) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL6962317 | 0.74 | RAB9A (0.44) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL6956305 | 0.72 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL29639431 | 0.67 | MAPK14 (0.50) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL28756187 | 0.67 | MAPK14 (0.50) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL18745595 | 0.66 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EMAPTCYP1A2 | |
| SCHEMBL3206476 | 0.66 | KMT2A (0.50) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL3195371 | 0.65 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL5337025 | 0.65 | ALDH1A1 (0.67) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL28698992 | 0.65 | CA1 (0.56) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998000402-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-01-08 | — | — | WO | disclosed |