SCHEMBL28698992

SCHEMBL28698992

NS(=O)(=O)c1ccccc1NC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 17/20 0.56
CA2 P00918 17/20 0.56
CA9 Q16790 3/20 0.50
CA12 O43570 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CA4 P22748 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17019166 0.88 CA2 (0.52) CA1CA2CA9CA12CA6
SCHEMBL3206476 0.86 KMT2A (0.50) MEN1KMT2A
SCHEMBL17019200 0.84 GAA (0.49) CA1CA2CA9CA12CA7
SCHEMBL20379649 0.83 HTR6 (0.53) MEN1KMT2A
SCHEMBL7481802 0.82 CA1 (0.61) CA1CA2CA9CA12CA6
SCHEMBL3195371 0.82 ALDH1A1 (0.49) MEN1KMT2A
SCHEMBL6118940 0.78 CA1 (0.69) CA1CA2CA9CA12CA6
SCHEMBL2653162 0.77 METAP2 (0.47) CA1CA2CA9CA12
SCHEMBL3359614 0.77 KMT2A (0.54) MEN1KMT2A
SCHEMBL10424370 0.77 NPC1 (0.57) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943234-A Preparation method of sulfonylphenylurea herbicide safener 常州大学 2022-01-18 CN disclosed