Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622194 | 0.84 | HIF1A (0.43) | SMN1; SMN2PTGS1PTGS2CYP2C19CYP2C9 | |
| SCHEMBL8621255 | 0.78 | ALOX5 (0.68) | — | |
| SCHEMBL8878016 | 0.76 | SLC6A3 (0.47) | KMT2AALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL1566474 | 0.72 | ALOX5 (0.51) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL17471247 | 0.71 | GAA (0.53) | GAACYP1A2 | |
| SCHEMBL6984545 | 0.71 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL10955566 | 0.70 | TSHR (0.46) | MEN1KMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL1985353 | 0.69 | GAA (0.51) | GAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8827886 | 0.69 | SLC6A3 (0.50) | MEN1KMT2AEPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9099363 | 0.69 | MEN1 (0.43) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582908-B1 | 2-Substituted quinolylmethoxy-phenylacetic acid- and -benzylacyl derivatives, process for their preparation and their use as inhibitors of leukotriene synthesis | BAYER AG (DE) | 1998-05-27 | — | — | EP | disclosed |
| US-5597833-A | LEUKOTRIENE SYNTHESIS INHIBITORS FOR ANTIINFLAMMATORY AGENTS, RESPIRATORY SYSTEM DISORDERS, ANTIALLERGENS OR ANTIISCHEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0582908-A1 | 2-Substituted guinolylmethoxy-phenylacetic acid derivatives, process for their preparation and their pharmaceutical use | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |