Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849979 | 0.78 | TSHR (0.48) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL7100679 | 0.75 | POLB (0.55) | MEN1KMT2AALDH1A1TSHRNPC1 | |
| SCHEMBL6987350 | 0.74 | MEN1 (0.45) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL8827886 | 0.74 | SLC6A3 (0.50) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8625795 | 0.71 | MEN1 (0.43) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL29577035 | 0.70 | GRIN2D (0.48) | MEN1KMT2ATSHRRAB9A | |
| SCHEMBL7098532 | 0.70 | POLB (0.47) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL14862759 | 0.70 | KMT2A (0.45) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL6703810 | 0.69 | MAPT (0.48) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL5730137 | 0.69 | CYP1A2 (0.44) | MEN1KMT2AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |