SCHEMBL8626064

SCHEMBL8626064

CS(=O)(=O)Oc1cc2ccc(S(=O)(=O)Cl)cc2cc1OS(C)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.36
LMNA P02545 2/20 0.35
TDP1 Q9NUW8 3/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
AKR1C3 P42330 2/20 0.34
AKR1C2 P52895 2/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP7 P09237 1/20 0.33
MMP9 P14780 1/20 0.33
MMP14 P50281 1/20 0.33
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328500 0.84 POLB (0.48) L3MBTL1LMNATDP1HTTSMN1; SMN2
SCHEMBL10983376 0.80 TDP1 (0.46) L3MBTL1LMNATDP1HTTSMN1; SMN2
SCHEMBL2263563 0.80 LMNA (0.48) L3MBTL1LMNATDP1SMN1; SMN2AKR1C3
SCHEMBL30357699 0.80 LMNA (0.48) L3MBTL1LMNATDP1SMN1; SMN2AKR1C3
SCHEMBL11667918 0.79 GAA (0.43) L3MBTL1LMNATDP1HTTSMN1; SMN2
SCHEMBL4180377 0.79 TSHR (0.56) LMNAHTTSMN1; SMN2ALDH1A1CA12
SCHEMBL307756 0.79 PTGS2 (0.40) LMNAHTTSMN1; SMN2MEN1KMT2A
SCHEMBL9787566 0.78 CA12 (0.46) L3MBTL1TDP1MEN1KMT2AALDH1A1
SCHEMBL30615201 0.78 LMNA (0.46) L3MBTL1LMNATDP1SMN1; SMN2ATM
SCHEMBL2263247 0.78 LMNA (0.46) L3MBTL1LMNATDP1SMN1; SMN2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736297-A Positive-working radiation-sensitive mixture and recording material produced therewith CLARIANT GMBH (DE) 1998-04-07 US disclosed