SCHEMBL2263247

SCHEMBL2263247

O=S(=O)(Cl)c1ccc2ccc(S(=O)(=O)Cl)cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.42
F2 P00734 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
PRSS3 P35030 1/20 0.38
MCOLN3 Q8TDD5 2/20 0.37
TSHR P16473 2/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30615201 1.00 LMNA (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL30357699 0.92 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL2263563 0.92 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL31387939 0.89 CYP2A6 (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL5730048 0.89 CYP2A6 (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL25642 0.88 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL29391838 0.88 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL1771133 0.87 MEN1 (0.47) LMNAHSD17B10TDP1TSHRCA1
SCHEMBL3566280 0.87 CYP2A6 (0.45) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL31468156 0.87 CYP2A6 (0.45) LMNAALDH1A1HSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US claimed
CN-114614058-B Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-114432903-B Composite membrane with acid resistance and preparation method and application thereof 中国石油化工股份有限公司 2023-03-14 CN claimed
CN-114984785-A Composite nanofiltration membrane and preparation method and application thereof 中国科学院过程工程研究所 2022-09-02 CN claimed
CN-114614058-A Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2022-06-10 CN claimed
CN-114432903-A Composite membrane with acid resistance and preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-113083035-B Ultra-low pressure composite nanofiltration membrane and preparation method thereof 江南大学 2022-02-08 CN claimed
CN-113083035-A Ultra-low pressure composite nanofiltration membrane and preparation method thereof 江南大学 2021-07-09 CN claimed
CN-112713361-A Composite lithium-sulfur battery diaphragm and preparation method and application thereof 中国石油化工股份有限公司 2021-04-27 CN claimed
CN-111686592-A Composite nanofiltration membrane and preparation method thereof 湖州欧美新材料有限公司 2020-09-22 CN claimed
CN-111615522-A Process for the synthesis of cyclodextrin derivatives 摩迪康公司 2020-09-01 CN claimed
CN-106964262-B Nanofiber-based pervaporation composite membrane and preparation method thereof 东华大学 2020-08-11 CN claimed
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US disclosed
US-20240383845-A1 NAPHTHALENEDITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION PROCESS AND USE FOR THE SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-11-21 US disclosed
US-20240217926-A1 1,6-NAPHTHALENEDITHIOL PRODUCT AND PROCESS FOR PRODUCING THE SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-07-04 US disclosed
EP-4378928-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-06-05 EP disclosed
US-4051106-A High molecular weight copolyester resins having a high degree of alternating structure HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-09-27 US disclosed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 US disclosed
US-4049629-A PREPARING POLYESTERS BY REACTING A DIACID HALIDE AND A SUBSTITUTED BISPHENOL AND A GLYCOL HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-09-20 US disclosed
US-3944526-A N-cyanosulfonamide resins and intermediates therefor and products thereof CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217926-A1 1,6-NAPHTHALENEDITHIOL PRODUCT AND PROCESS FOR PRODUCING THE SAME SULT1A1, SULT2A1, DNTT LMNA 2339/4885ALDH1A1 386/4885HSD17B10 312/4885
US-20240383845-A1 NAPHTHALENEDITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION PROCESS AND USE FOR THE SAME HSD11B1, DHCR7, CYP17A1 LMNA 2311/4885ALDH1A1 297/4885HSD17B10 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.