SCHEMBL862637

SCHEMBL862637

Cc1ccc(-c2c(C)c(C)c(-c3ccc(C)s3)c3nsnc23)s1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
NPC1 O15118 2/20 0.37
HSD17B10 Q99714 2/20 0.37
GFER P55789 1/20 0.37
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14123536 0.84 ALDH1A1 (0.43) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL15249165 0.84 ALDH1A1 (0.35) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL24347886 0.82 ALDH1A1 (0.38) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL20163207 0.82 MAPT (0.36) ALDH1A1MAPTNPC1HSD17B10MEN1
SCHEMBL14123554 0.81 MAPT (0.33) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL13024231 0.81 NPC1 (0.34) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL21627163 0.80 KDM4E (0.36) ALDH1A1KDM4EHPGD
SCHEMBL25450958 0.80 NPC1 (0.33) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL19602884 0.80 ALDH1A1 (0.45) ALDH1A1MAPTNPC1HSD17B10GFER
SCHEMBL25450890 0.80 NPC1 (0.33) ALDH1A1MAPTNPC1HSD17B10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325225-B1 Complex aryl copolymer compounds and polymer light emitting devices made by using the same SUMITOMO CHEMICAL CO (JP) 2016-06-15 EP disclosed
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
US-9179518-B2 Light emissive device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-11-03 US disclosed
US-9136477-B2 Light emissive device CDT OXFORD LIMITED (GB) 2015-09-15 US disclosed
US-9028715-B2 Compositions and methods for manufacturing light-emissive devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-05-12 US disclosed
US-8981365-B2 Organic light emissive device comprising a trilayer cathode including a layer comprising sodium fluoride CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-03-17 US disclosed
US-8878163-B2 Light-emitting device and 9.9 biphenyl fluorene materials therefor CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-11-04 US disclosed
US-8648334-B2 Organic light emissive device comprising a trilayer cathode CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-02-11 US disclosed
US-8440325-B2 Electronic device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-05-14 US disclosed
US-8399605-B2 Arylamine polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-03-19 US disclosed
US-20080309229-A1 Arylamine Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-12-18 US disclosed
US-20080197768-A1 Light Emissive Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2008-08-21 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed
US-7157154-B2 Organoboron polymers; photoconductivity; inks; thin films; semiconductors; surface light sources; dot matrix displays SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-02 US disclosed
US-7157154-B2 Organoboron polymers; photoconductivity; inks; thin films; semiconductors; surface light sources; dot matrix displays SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 ALDH1A1 4281/4885MAPT 4058/4885NPC1 1799/4885
US-20080309229-A1 Arylamine Polymer NAT1, AR, AHR ALDH1A1 627/4885MAPT 2625/4885NPC1 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.