Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623459 | 0.71 | NPC1 (0.36) | DYRK1ANPSR1 | |
| SCHEMBL8623456 | 0.69 | KDM4E (0.35) | — | |
| SCHEMBL9261326 | 0.67 | FFAR4 (0.33) | NFATC1GSK3BDYRK1A | |
| SCHEMBL89180 | 0.65 | EGFR (0.33) | — | |
| SCHEMBL8628232 | 0.65 | MMP9 (0.38) | NFATC1GSK3BDYRK1A | |
| SCHEMBL19252985 | 0.65 | SIRT3 (0.32) | — | |
| SCHEMBL8627275 | 0.64 | CYP3A4 (0.36) | — | |
| SCHEMBL9257345 | 0.64 | FFAR4 (0.33) | NFATC1GSK3BDYRK1A | |
| SCHEMBL8629913 | 0.61 | CA12 (0.31) | — | |
| SCHEMBL6617958 | 0.61 | CA12 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |