Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562486 | 0.80 | CYP3A4 (0.33) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL8623666 | 0.74 | L3MBTL1 (0.35) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL8625791 | 0.71 | ALDH1A1 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL27506106 | 0.67 | — | — | |
| SCHEMBL27490066 | 0.66 | CA12 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL27491838 | 0.63 | CA12 (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL8627275 | 0.63 | CYP3A4 (0.36) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL8556566 | 0.63 | GRIA2 (0.35) | CA12CA1CA2CA9CYP3A4 | |
| SCHEMBL8626449 | 0.61 | NFATC1 (0.34) | — | |
| SCHEMBL8623946 | 0.61 | CA12 (0.38) | CA12CA1CA2CA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |