Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | PTGIR | P43119 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626475 | 0.82 | PTGIR (0.57) | GAASIGMAR1PTGIRALDH1A1MAPT | |
| SCHEMBL8626228 | 0.82 | PTGIR (0.57) | GAASIGMAR1PTGIRALDH1A1MAPT | |
| SCHEMBL8626755 | 0.81 | PTGIR (0.42) | GAATBXA2RSIGMAR1PTGIRALDH1A1 | |
| SCHEMBL9048482 | 0.70 | PTGIR (0.48) | SIGMAR1PTGIR | |
| SCHEMBL9427205 | 0.70 | PTGIR (0.69) | SIGMAR1PTGIR | |
| SCHEMBL9048207 | 0.70 | PTGIR (0.46) | GAASIGMAR1PTGIRALDH1A1 | |
| SCHEMBL9427485 | 0.69 | PTGIR (0.45) | SIGMAR1PTGIR | |
| SCHEMBL9048041 | 0.69 | PTGIR (0.47) | SIGMAR1PTGIR | |
| SCHEMBL9048014 | 0.69 | PTGIR (0.43) | SIGMAR1PTGIRALDH1A1 | |
| SCHEMBL9048344 | 0.69 | PTGIR (0.45) | GAASIGMAR1PTGIRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |