Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5,6-Dihydroxy-8-Aminoquinoline SCHEMBL5640903 | 0.85 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL9308262 | 0.79 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL1133269 | 0.77 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL2355988 | 0.75 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL18455869 | 0.75 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL8627392 | 0.74 | NSD2 (0.72) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL7915022 | 0.73 | NR4A2 (0.55) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL688655 | 0.73 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL29721839 | 0.73 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL13313357 | 0.73 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614915-B1 | Polymer scale preventive agent | SHINETSU CHEMICAL CO (JP) | 1998-06-24 | — | — | EP | disclosed |
| US-5420214-A | Process to prevent scale adhesion using condensation product of a diamino heterocyclic and a quinone | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0614915-A1 | Polymer scale preventive agent | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-09-14 | — | — | EP | disclosed |