Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 4/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15149564 | 0.81 | CYP3A4 (0.50) | EPHX2CYP3A4TSHR | |
| SCHEMBL19027635 | 0.80 | SYK (0.50) | SYKCTSLPPARAKLK7KLK5 | |
| SCHEMBL18431051 | 0.80 | SYK (0.50) | SYKCTSLPPARAKLK7KLK5 | |
| SCHEMBL5353977 | 0.79 | KLK7 (0.54) | SYKCTSLPPARAKLK7KLK5 | |
| SCHEMBL30252216 | 0.79 | CYP3A4 (0.55) | MAPTATMCYP3A4TSHR | |
| SCHEMBL14768576 | 0.79 | CTSL (0.51) | SYKCTSLPPARAKLK7KLK5 | |
| SCHEMBL27978333 | 0.78 | KMT2A (0.48) | CTSSEPHX2CTSK | |
| SCHEMBL15535916 | 0.78 | KMT2A (0.48) | CTSSEPHX2CTSK | |
| SCHEMBL8299304 | 0.78 | KMT2A (0.48) | CTSSEPHX2CTSK | |
| SCHEMBL31045519 | 0.76 | CYP3A4 (0.52) | ATMCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560274-B1 | Antiherpes peptide derivatives having a ureido N-terminus | BOEHRINGER INGELHEIM CA LTD (CA) | 1998-06-24 | — | — | EP | disclosed |
| EP-0560274-A1 | Antiherpes peptide derivatives having a ureido N-terminus | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-15 | — | — | EP | disclosed |