⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757721 | 0.69 | S1PR3 (0.42) | — | |
| SCHEMBL4757920 | 0.68 | S1PR3 (0.41) | — | |
| SCHEMBL8628308 | 0.68 | — | — | |
| SCHEMBL24328842 | 0.64 | CTSA (0.40) | — | |
| SCHEMBL8628463 | 0.64 | — | — | |
| SCHEMBL24327736 | 0.64 | CTSA (0.40) | — | |
| SCHEMBL8627742 | 0.64 | GLS (0.31) | — | |
| SCHEMBL3827990 | 0.64 | C3AR1 (0.34) | — | |
| SCHEMBL23424110 | 0.59 | NR4A2 (0.37) | — | |
| SCHEMBL24328853 | 0.58 | IMPDH2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4183925-A | 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use | PFIZER INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4144240-A | USED FOR MODIFYING CEPHALOSPORINS | PFIZER INC. (US) | 1979-03-13 | — | — | US | disclosed |