SCHEMBL8626752

SCHEMBL8626752

Cc1cccc(Oc2ccc(C(=O)O)cc2)c1Oc1ccc(C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 11/20 0.58
LPAR5 Q9H1C0 11/20 0.58
RXRA P19793 2/20 0.50
SRD5A2 P31213 2/20 0.49
RXRB P28702 1/20 0.48
RXRG P48443 1/20 0.48
PARP15 Q460N3 1/20 0.46
PARP10 Q53GL7 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TTR P02766 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
CRHBP P24387 1/20 0.45
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
CRHR2 Q13324 1/20 0.45
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11602793 0.91 LPAR1 (0.52) LPAR1LPAR5RXRASRD5A2RXRB
SCHEMBL10685959 0.90 LPAR1 (0.68) LPAR1LPAR5RXRASRD5A2PARP15
SCHEMBL8746017 0.85 LPAR1 (0.70) LPAR1LPAR5RXRASRD5A2RXRB
SCHEMBL15011665 0.84 LPAR1 (0.54) LPAR1LPAR5RXRASRD5A2RXRB
SCHEMBL11603272 0.83 LPAR1 (0.68) LPAR1LPAR5RXRASRD5A2RXRB
SCHEMBL24407669 0.83 LPAR1 (0.56) LPAR1LPAR5RXRASRD5A2PARP15
SCHEMBL16506673 0.83 LPAR1 (0.63) LPAR1LPAR5SRD5A2PARP15PARP10
SCHEMBL1345933 0.81 LTA4H (0.44) ALDH1A1GAAHPGDHTT
SCHEMBL8628620 0.81 LPAR1 (0.58) LPAR1LPAR5SRD5A2PARP10TTR
SCHEMBL8627947 0.80 POLB (0.51) ALDH1A1POLBGAACRHBPFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed