Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.70 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.70 |
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603272 | 0.98 | LPAR1 (0.68) | LPAR1LPAR5RXRARXRBRXRG | |
| SCHEMBL7706043 | 0.87 | SRD5A2 (0.68) | LPAR1LPAR5SRD5A2TTRCA1 | |
| SCHEMBL5608673 | 0.86 | HPGD (0.62) | LPAR1LPAR5MAPK14EZH2PARP10 | |
| Hydrochloric Acid SCHEMBL8433842 | 0.85 | SRD5A2 (0.66) | LPAR1LPAR5SRD5A2TTRCA1 | |
| Hydrochloric Acid SCHEMBL8433836 | 0.85 | SRD5A2 (0.66) | LPAR1LPAR5SRD5A2TTRCA1 | |
| SCHEMBL15011665 | 0.85 | LPAR1 (0.54) | LPAR1LPAR5RXRARXRBRXRG | |
| SCHEMBL8626752 | 0.85 | LPAR1 (0.58) | LPAR1LPAR5RXRARXRBRXRG | |
| SCHEMBL11604084 | 0.84 | LPAR1 (0.53) | LPAR1LPAR5MAPK14EZH2PARP10 | |
| SCHEMBL11602631 | 0.84 | PARP10 (0.66) | LPAR1LPAR5MAPK14EZH2CA1 | |
| SCHEMBL16507467 | 0.84 | LPAR1 (1.00) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673724-A | FROM P-OXYBENZOYL AND 2-OXY-6-NAPHTHOYL COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | claimed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | claimed |
| US-20220146935-A1 | CARBOXYLATE, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20190010129-A1 | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2019-01-10 | — | — | US | disclosed |
| US-10100018-B2 | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-16 | — | — | US | disclosed |
| US-9464060-B2 | Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20160207880-A1 | AMIDE DERIVATIVES AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-21 | — | — | US | disclosed |
| CN-105473548-A | Amide derivatives as lysophosphatidic acid receptor antagonists | TAKEDA PHARMACEUTICALS CO | 2016-04-06 | — | — | CN | disclosed |
| US-20150057298-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2015-02-26 | — | — | US | disclosed |
| EP-0757702-A1 | POLY (IMIDE-ETHERS) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029948-A1 | POLY (IMIDE-ETHERS) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| US-4673724-A | FROM P-OXYBENZOYL AND 2-OXY-6-NAPHTHOYL COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1987-06-16 | — | — | US | disclosed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100018-B2 | Amide derivatives as lysophosphatidic acid receptor antagonists | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885LPAR5 5/4885RXRA 205/4885 |
| US-20190010129-A1 | Amide derivatives as lysophosphatidic acid receptor antagonists | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885LPAR5 5/4885RXRA 196/4885 |
| US-20160207880-A1 | AMIDE DERIVATIVES AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885LPAR5 5/4885RXRA 205/4885 |
| US-20150057298-A1 | NOVEL COMPOUNDS | F12, C1R, CHRM1 | LPAR1 421/4885LPAR5 1052/4885RXRA 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.