Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048344 | 0.94 | PTGIR (0.45) | PTGIRKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9049505 | 0.90 | KDM4C (0.41) | PTGIR | |
| SCHEMBL9050611 | 0.89 | KMT2A (0.44) | PTGIRKMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9051691 | 0.85 | PTGIR (0.46) | PTGIRSIGMAR1 | |
| SCHEMBL9051607 | 0.83 | KMT2A (0.43) | KMT2AL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9047961 | 0.83 | TBXAS1 (0.40) | PTGIRLMNA | |
| SCHEMBL9427205 | 0.81 | PTGIR (0.69) | PTGIRKDM4ESIGMAR1 | |
| SCHEMBL9567963 | 0.81 | ALDH1A1 (0.44) | PTGIRKMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9048216 | 0.81 | PTGIR (0.71) | PTGIRSIGMAR1 | |
| SCHEMBL9048210 | 0.81 | PTGIR (0.53) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |