Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Trolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.39 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | EYA2 | O00167 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL5874464 | 1.00 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Trolamine SCHEMBL6654624 | 0.97 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Trolamine SCHEMBL28237542 | 0.97 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Trolamine SCHEMBL11791924 | 0.92 | CAMK2A (0.46) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| SCHEMBL5067889 | 0.92 | CAMK2A (0.46) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| SCHEMBL563771 | 0.92 | CAMK2A (0.46) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Trolamine SCHEMBL5874784 | 0.89 | SLC22A6 (0.58) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Adipic Acid SCHEMBL5875290 | 0.89 | GPR84 (0.59) | LMNACAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL21513124 | 0.89 | TDP1 (0.43) | LMNAEGLN1ALKBH5SUCNR1CAMK2A | |
| Adipic Acid SCHEMBL11579435 | 0.89 | GPR84 (0.59) | LMNACAMK2AGPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115247096-A | High-safety harmless cutting fluid and preparation method thereof | 哈尔滨市力安特科技发展有限责任公司 | 2022-10-28 | — | — | CN | claimed |
| CN-112975200-B | High-stability environment-friendly soldering paste and preparation method thereof | 深圳市邦大科技有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-112975200-A | High-stability environment-friendly soldering paste and preparation method thereof | 深圳市邦大科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-108467349-B | Preparation of 3- (N, N-dimethyl-N-X) ammonium succinic acid triethanolamine triester triple salt surfactant | 天津工业大学 | 2020-10-02 | — | — | CN | claimed |
| CN-110423314-A | A kind of Early-strength polycarboxylate superplasticizer of the side group containing triethanolamine and preparation method thereof | YANCHENG INST TECH | 2019-11-08 | — | — | CN | claimed |
| CN-106825982-B | A kind of anti-collapse leadless soldering tin paste of low viscosity and preparation method thereof | 深圳市斯特纳新材料有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-109251782-A | Ultrathin rust-proof oil | 南宁凯林杰机械化工有限公司 | 2019-01-22 | — | — | CN | claimed |
| CN-106825982-A | A kind of anti-collapse leadless soldering tin paste of low viscosity and preparation method thereof | 深圳市斯特纳新材料有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-104476007-B | A kind of high-melting point lead-free halogen-free soldering tin paste and preparation method thereof | DONGGUAN YONG AN TECHNOLOGY CO., LTD. (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-104476007-A | High-melting-point lead-free and halogen-free soldering paste and preparing method of high-melting-point lead-free and halogen-free soldering paste | DONGGUAN YONG AN TECHNOLOGY CO LTD | 2015-04-01 | — | — | CN | claimed |
| US-5712232-A | ANIONIC SURFACTANT AND A SALT | KAO CORPORATION (JP) | 1998-01-27 | — | — | US | claimed |
| EP-0131826-B1 | STORAGE-STABLE UNIVERSAL CONTROL SERUM | Roche Diagnostics GmbH (DE) | 1987-11-19 | — | — | EP | claimed |
| EP-0131826-A1 | Storage-stable universal control serum | Roche Diagnostics GmbH (DE) | 1985-01-23 | — | — | EP | claimed |
| CN-121202651-A | Low-temperature environment resistant long-distance conveying upward Kong Ruhua granular ammonium nitrate fuel oil explosive and preparation method thereof | 朝阳红山化工有限责任公司 | 2025-12-26 | — | — | CN | disclosed |
| CN-118373930-A | Preparation method of emulsion explosive high-molecular emulsifier and hydroxyl value measurement method | 辽宁红山化工股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-117567774-A | Preparation method of antibacterial polymer film | 苏州新众源智能科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-4752340-A | SURFACE TREATMENT WITH AN AMINE SALT OF A POLYPROTIC ACID | KERR-MCGEE CHEMICAL CORPORATION (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0131826-B1 | STORAGE-STABLE UNIVERSAL CONTROL SERUM | Roche Diagnostics GmbH (DE) | 1987-11-19 | — | — | EP | disclosed |
| EP-0131826-A1 | Storage-stable universal control serum | Roche Diagnostics GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4328111-A | CORROSION INHIBITION | STANDARD OIL COMPANY (INDIANA) (US) | 1982-05-04 | — | — | US | disclosed |