Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914219 | 0.75 | TDP1 (0.48) | ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA | |
| SCHEMBL7994013 | 0.71 | MAOB (0.54) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15043883 | 0.70 | MAOB (0.52) | MAOBSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL1091737 | 0.69 | MAOB (0.62) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2450743 | 0.67 | MAOB (0.77) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8918012 | 0.66 | MIF (0.47) | ALDH1A1HTTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6347635 | 0.65 | MAOB (0.59) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL20897875 | 0.65 | MAPT (0.54) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL42302 | 0.65 | MAOB (1.00) | MAOBALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5035686 | 0.65 | MAOB (0.59) | MAOBCASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |