SCHEMBL8626962

CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)(C)CCO[Si](C(C)C)(C(C)C)C(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	19/20	0.42

▸	CAPN1	P07384	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4046077	0.80	CAPN1 (0.51)	RENCAPN1
SCHEMBL4046079	0.80	CAPN1 (0.51)	RENCAPN1
SCHEMBL8565477	0.77	CA1 (0.38)	—
SCHEMBL8565474	0.77	CA1 (0.38)	—
SCHEMBL8569499	0.75	CYP2D6 (0.39)	REN
SCHEMBL8561160	0.75	CA1 (0.36)	REN
SCHEMBL8561163	0.75	CA1 (0.36)	REN
SCHEMBL8569503	0.75	CYP2D6 (0.39)	REN
SCHEMBL8906152	0.72	REN (0.70)	REN
SCHEMBL8563890	0.70	CA1 (0.38)	CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5719141-A	HYPOTENSIVE AGENTS	NOVARTIS CORPORATION (US)	1998-02-17	—	—	US	disclosed