SCHEMBL8627156

SCHEMBL8627156

Nc1cc(N)nc(S(=O)(=O)O)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 5/20 0.36
TSHR P16473 3/20 0.36
NT5E P21589 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 4/20 0.35
CYP2C19 P33261 3/20 0.34
CASP6 P55212 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP1A2 P05177 1/20 0.33
BLM P54132 1/20 0.33
NSD2 O96028 1/20 0.32
DUSP3 P51452 1/20 0.32
PTPN5 P54829 1/20 0.32
PTPN11 Q06124 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27323912 0.85 ALDH1A1 (0.33) KDM4EALDH1A1TSHRNT5ETDP1
Sulfuric Acid SCHEMBL8723533 0.75 MAPT (0.36) KDM4EALDH1A1TSHRNT5ETDP1
SCHEMBL3634528 0.74 CA5A (0.36) TSHRNT5ETDP1HSD17B10CYP2C19
SCHEMBL9395961 0.74 CYP1A2 (0.36) KDM4EALDH1A1TSHRNT5EHSD17B10
SCHEMBL27976239 0.74 TSHR (0.33) KDM4EALDH1A1TSHRNT5EHSD17B10
SCHEMBL27911490 0.73 KDM4E (0.42) KDM4EALDH1A1TSHRNT5ETDP1
SCHEMBL5929087 0.70 HTT (0.39) KDM4EALDH1A1TSHRTDP1MAPT
SCHEMBL8625405 0.70 CA12 (0.38) KDM4EALDH1A1TSHRNT5ETDP1
SCHEMBL27344993 0.70 NOS3 (0.37) ALDH1A1TDP1NOS3NOS1NOS2
SCHEMBL27903828 0.69 NT5E (0.35) KDM4EALDH1A1TSHRNT5ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614915-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-06-24 EP claimed
US-5420214-A Process to prevent scale adhesion using condensation product of a diamino heterocyclic and a quinone SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-30 US claimed
EP-0614915-A1 Polymer scale preventive agent Shin-Etsu Chemical Co., Ltd. (JP) 1994-09-14 EP claimed
EP-0614915-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-06-24 EP disclosed
US-5420214-A Process to prevent scale adhesion using condensation product of a diamino heterocyclic and a quinone SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-30 US disclosed
EP-0614915-A1 Polymer scale preventive agent Shin-Etsu Chemical Co., Ltd. (JP) 1994-09-14 EP disclosed