Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297735 | 0.81 | PI4KA (0.55) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15499106 | 0.81 | TK1 (0.50) | ALDH1A1 | |
| SCHEMBL15499151 | 0.78 | PTPN1 (0.40) | — | |
| SCHEMBL22359200 | 0.78 | ADCY5 (0.57) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4557505 | 0.77 | PI4KA (0.51) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4557507 | 0.77 | PI4KA (0.51) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3578046 | 0.76 | ALDH1A1 (0.44) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23860004 | 0.76 | ARG1 (0.49) | ALDH1A1 | |
| SCHEMBL23860001 | 0.76 | ARG1 (0.49) | ALDH1A1 | |
| SCHEMBL6045649 | 0.76 | ADORA2A (0.62) | ALDH1A1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705333-A | Peptide-based nucleic acid mimics(PENAMS) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1996004000-A1 | PEPTIDE-BASED NUCLEIC ACID MIMICS (PENAMs) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-02-15 | — | — | WO | disclosed |