Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39548 | 0.87 | CYP1A2 (0.39) | — | |
| SCHEMBL7094303 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL20751502 | 0.76 | — | — | |
| SCHEMBL10987812 | 0.74 | — | — | |
| SCHEMBL11336233 | 0.71 | CYP1A2 (0.43) | FDPS | |
| SCHEMBL14473861 | 0.71 | CYP1A2 (0.43) | FDPS | |
| SCHEMBL14504926 | 0.71 | CYP1A2 (0.43) | FDPS | |
| SCHEMBL23542637 | 0.67 | — | — | |
| SCHEMBL75236 | 0.67 | — | — | |
| SCHEMBL10306785 | 0.67 | FDPS (0.33) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846108-A1 | AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS | NEUROCRINE BIOSCIENCES, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996039400-A1 | AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS | NEUROCRINE BIOSCIENCES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |