Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627431 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL3530470 | 0.78 | KDM4E (0.59) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL3529280 | 0.78 | KDM4E (0.59) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL3529276 | 0.78 | KDM4E (0.59) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL25753399 | 0.76 | RAB9A (0.58) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL1980663 | 0.76 | RAB9A (0.58) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL1081956 | 0.76 | RAB9A (0.58) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8628699 | 0.76 | FBP1 (0.56) | MAPTLMNAHTTKDM4ECYP1A2 | |
| SCHEMBL8628697 | 0.76 | FBP1 (0.56) | MAPTLMNAHTTKDM4ECYP1A2 | |
| SCHEMBL27494494 | 0.76 | KDM4E (0.57) | MAPTSMN1; SMN2LMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |