SCHEMBL8627562

SCHEMBL8627562

CC=CC(=O)OC(CCC)O[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32
GSTP1 P09211 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28282181 0.86 HCAR2 (0.38) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL28071076 0.81 TSHR (0.38)
SCHEMBL28283798 0.75 SMPD1 (0.43) HCAR2
SCHEMBL27515974 0.73 HCAR2 (0.36) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL9068912 0.73 HCAR2 (0.36) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL4613185 0.73 HCAR2 (0.32) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL4613181 0.73 HCAR2 (0.32) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL27938679 0.72 PRKCA (0.41) HCAR2GSTP1TAS1R3TAS1R1
SCHEMBL1403514 0.71 ALDH1A1 (0.38)
SCHEMBL5831229 0.71 HCAR2 (0.42) HCAR2TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807914-A POLYCARBONATE OLIGOMER, POLYSILOXANE-POLYACRYLATE COMPOSITE RUBBER GRAFTED WITH ACRYLONITRILE AND STYRENE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1998-09-15 US disclosed