SCHEMBL8627633

SCHEMBL8627633

O=C=NC(C(=O)O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.46
CYP2D6 P10635 1/20 0.46
LMNA P02545 3/20 0.45
MAPK1 P28482 1/20 0.45
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
GRM2 Q14416 1/20 0.38
GRM3 Q14832 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3578270 1.00 SRC (0.46) SRCCYP2D6LMNAMAPK1CES2
SCHEMBL28066129 0.84 SRC (0.43) SRCGRM2TDP1CYP2C19
SCHEMBL11626465 0.82 MIF (0.52) SRCCYP2D6LMNAMAPK1CES2
SCHEMBL29036003 0.80 KMT2A (0.55) CYP2D6LMNAMAPK1CYP1A2
SCHEMBL8853888 0.80 KMT2A (0.55) CYP2D6LMNAMAPK1CYP1A2
SCHEMBL16192842 0.79 MIF (0.36) SRCCYP2D6LMNAMAPK1
SCHEMBL988808 0.79 HPGD (0.42) SRCCYP2D6LMNA
SCHEMBL43325 0.78 SRC (0.42) SRCCYP2D6LMNAMAPK1CES2
SCHEMBL10425174 0.78 SRC (0.54) SRCCYP2D6LMNAMAPK1CES2
SCHEMBL11623603 0.78 SRC (0.54) SRCCYP2D6LMNAMAPK1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117054585-A Charged surface reversed phase chromatography material method for analysis of glycans modified with amphiphilic strong basic moieties 沃特世科技公司 2023-11-14 CN disclosed
CN-109154604-B Charged surface reversed phase chromatography material method for analysis of glycans modified with amphiphilic strong basic moieties 沃特世科技公司 2023-07-21 CN disclosed
WO-2022145400-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS 三光株式会社 2022-07-07 WO disclosed
EP-0679161-B1 THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME RHONE POULENC RORER SA (FR) 1998-06-24 EP disclosed
US-4128724-A MICROBIOCIDE E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4128723-A BACTERICIDE E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4096329-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1978-06-20 US disclosed
US-4091212-A ANTIMICROBIAL E. R. SQUIBB & SONS, INC. (US) 1978-05-23 US disclosed
US-4038271-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1977-07-26 US disclosed
US-3994886-A ANTIBACTERIAL RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) 1976-11-30 US disclosed
US-3994887-A ANTIBACTERIAL RECHERCHE ET INDUSTRIE THERAPEUTIQUES (R.I.T.) (BE) 1976-11-30 US disclosed