SCHEMBL988808

SCHEMBL988808

C=C(C)C(N=C=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
MIF P14174 3/20 0.36
ADRA2A P08913 1/20 0.34
ADRA2C P18825 1/20 0.34
LMNA P02545 1/20 0.34
HIF1A Q16665 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NOS2 P35228 1/20 0.34
CYP2D6 P10635 1/20 0.33
SRC P12931 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6536411 0.89 ALDH1A1 (0.41) HPGDADRA2AADRA2CLMNAHIF1A
SCHEMBL16192842 0.81 MIF (0.36) HPGDMIFADRA2AADRA2CLMNA
SCHEMBL3909040 0.80 HPGD (0.37) HPGDMIFADRA2AADRA2CLMNA
SCHEMBL8627633 0.79 SRC (0.46) LMNACYP2D6SRC
SCHEMBL3578270 0.79 SRC (0.46) LMNACYP2D6SRC
SCHEMBL6323425 0.77 HPGD (0.39) HPGDMIFNOS2CYP2D6SRC
SCHEMBL4455459 0.77 ACP3 (0.39) HPGDLMNAALDH1A1KMT2A
SCHEMBL29036003 0.75 KMT2A (0.55) LMNACYP2D6ALDH1A1KMT2A
SCHEMBL8853888 0.75 KMT2A (0.55) LMNACYP2D6ALDH1A1KMT2A
SCHEMBL28477637 0.74 MIF (0.41) HPGDMIFLMNAKDM4ENOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137527-B1 STABILIZER FOR POLYMER POLYOL PRODUCTION PROCESSES BASF SE (DE) 2023-11-22 EP claimed
US-10590302-B2 High solids, low viscosity urethane-linkage containing latex and method of production thereof ARKEMA INC. (US) 2020-03-17 US claimed
US-10472458-B2 Stabilizer for polymer polyol production processes BASF SE (DE) 2019-11-12 US claimed
US-10294336-B2 Synthesis of polymer polyols in unsaturated polyols, polymer polyols and their use BASF SE (DE) 2019-05-21 US claimed
US-20170130093-A1 HIGH SOLIDS, LOW VISCOSITY URETHANE-LINKAGE CONTAINING LATEX AND METHOD OF PRODUCTION THEREOF ARKEMA INC. 2017-05-11 US claimed
EP-3157963-A1 HIGH SOLIDS, LOW VISCOSITY URETHANE-LINKAGE CONTAINING LATEX AND METHOD OF PRODUCTION THEREOF Arkema, Inc. (US) 2017-04-26 EP claimed
EP-3137527-A1 STABILIZER FOR POLYMER POLYOL PRODUCTION PROCESSES BASF SE (DE) 2017-03-08 EP claimed
US-20170051097-A1 STABILIZER FOR POLYMER POLYOL PRODUCTION PROCESSES BASF SE (DE) 2017-02-23 US claimed
CN-106459254-A High-solid, low-viscosity urethane-linker-containing latex and method for producing same 阿科玛股份有限公司 2017-02-22 CN claimed
WO-2015195466-A1 HIGH SOLIDS, LOW VISCOSITY URETHANE-LINKAGE CONTAINING LATEX AND METHOD OF PRODUCTION THEREOF ARKEMA INC. (US) 2015-12-23 WO claimed
JP-2004500458-A 2004-01-08 JP claimed
EP-1312334-A2 Cosmetic compositions containing aminosilicone and a thickening agent and their use L'OREAL (FR) 2003-05-21 EP claimed
EP-1312333-A2 Cosmetic compositions containing aminosilicone and a thickening agent and their use L'OREAL (FR) 2003-05-21 EP claimed
EP-1115750-A4 AQUEOUS COMPOSITION ROHM & HAAS (US) 2002-05-22 EP claimed
CN-1325675-A Vinyl polydimethyl siloxanes/polydimethy siloxanes copolymer and thickening agent cosmetic compositions and use thereof OREAL (FR) 2001-12-12 CN claimed
WO-2001057047-A1 ZWITTERIONIC GROUPS CONTAINING COMPOUNDS FROM MICHAEL-TYPE REACTIONS USEFUL AS MONOMERS AND MACROMERS BIOCOMPATIBLES UK LIMITED (GB) 2001-08-09 WO claimed
EP-1115750-A1 AQUEOUS COMPOSITION ROHM AND HAAS COMPANY (US) 2001-07-18 EP claimed
EP-1108416-A1 Cosmetic aqueous emulsion compositions containing a vinyldimethicone/dimethicone copolymer and an associative thickener and their uses L'OREAL (FR) 2001-06-20 EP claimed
WO-2000005272-A1 AQUEOUS COMPOSITION ROHM AND HAAS COMPANY (US) 2000-02-03 WO claimed
EP-0203361-A2 Improved polyester resin gelkote composition THE GLIDDEN COMPANY (formerly known as ATKEMIX EIGHT INC.) (US) 1986-12-03 EP claimed