Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629907 | 0.83 | KDM4E (0.37) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8630018 | 0.73 | ALDH1A1 (0.65) | MAPTALDH1A1LMNAGSK3BNPSR1 | |
| SCHEMBL8632018 | 0.73 | GAA (0.54) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL10935147 | 0.72 | HDAC1 (0.43) | KMT2AMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL5010509 | 0.72 | GSK3B (0.59) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8650621 | 0.71 | MEN1 (0.53) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8631463 | 0.71 | DAO (0.53) | ALDH1A1KDM4EGSK3B | |
| SCHEMBL9777829 | 0.71 | MEN1 (0.52) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8651250 | 0.70 | GSK3B (0.61) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL899479 | 0.70 | GSK3B (0.61) | MEN1KMT2AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |