SCHEMBL8627685

SCHEMBL8627685

COc1ccc(S(=O)(=O)NC(=O)NCc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
CYP2C9 P11712 1/20 0.64
EGFR P00533 1/20 0.60
ERBB2 P04626 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 1/20 0.59
SGMS1 Q86VZ5 1/20 0.57
PKM P14618 1/20 0.56
POLB P06746 1/20 0.56
TSHR P16473 1/20 0.55
MAPT P10636 1/20 0.55
NAMPT P43490 2/20 0.55
CXCR3 P49682 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6467702 0.91 CYP19A1 (0.67) ALDH1A1CYP2C9EGFRERBB2SMN1; SMN2
SCHEMBL5186630 0.85 ALDH1A1 (0.75) ALDH1A1CYP2C9SMN1; SMN2TSHRMAPT
SCHEMBL6467327 0.83 ALDH1A1 (0.57) ALDH1A1CYP2C9EGFRERBB2SMN1; SMN2
SCHEMBL3296646 0.83 NPC1 (0.61) ALDH1A1CYP2C9NPC1RAB9ASGMS1
SCHEMBL16562080 0.82 NPC1 (0.77) ALDH1A1CYP2C9SMN1; SMN2NPC1RAB9A
SCHEMBL595420 0.82 CYP2C9 (0.69) ALDH1A1CYP2C9SMN1; SMN2TSHRMAPT
SCHEMBL6464484 0.81 SMN1; SMN2 (0.50) ALDH1A1EGFRERBB2SMN1; SMN2RAB9A
SCHEMBL6468804 0.80 ALDH1A1 (0.61) ALDH1A1CYP2C9EGFRERBB2SMN1; SMN2
SCHEMBL120702 0.80 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2PKMPOLBTSHR
SCHEMBL7777663 0.79 LMNA (0.71) ALDH1A1CYP2C9EGFRERBB2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0738610-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-17 EP disclosed
EP-0615859-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0738610-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1996-10-23 EP disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed