Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628320 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL8625712 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL1905016 | 0.71 | KDM4E (0.45) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL14076990 | 0.70 | RAB9A (0.54) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL8631747 | 0.69 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL1544366 | 0.68 | RAB9A (0.51) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL4398242 | 0.66 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL9789735 | 0.66 | HSD17B10 (0.54) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL4036616 | 0.64 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL8629186 | 0.64 | NPC1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |