SCHEMBL702316

SCHEMBL702316

COc1ccccc1OP(=O)(O)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.48
FAAH O00519 3/20 0.48
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
P2RX7 Q99572 1/20 0.45
GPR84 Q9NQS5 1/20 0.44
EPHX2 P34913 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27495160 0.80 SRC (0.46) CNR2FAAHKMT2AP2RX7EPHX2
SCHEMBL5145096 0.78 GPR84 (0.41) CNR2FAAHKMT2AMEN1P2RX7
SCHEMBL28621325 0.77 CA1 (0.56) KMT2AMEN1GPR84LMNAHTT
SCHEMBL8627735 0.75 SRC (0.41) CNR2FAAHKMT2AP2RX7EPHX2
SCHEMBL24897195 0.75 GPR84 (0.79) GPR84
SCHEMBL17169179 0.73 NPSR1 (0.61) KMT2AMEN1EPHX2NPSR1SIGMAR1
SCHEMBL6859389 0.71 MEN1 (0.39) CNR2FAAHKMT2AMEN1P2RX7
SCHEMBL30770359 0.69 INPPL1 (0.57) KMT2AMEN1LMNAHTT
SCHEMBL19808 0.69 INPPL1 (0.57) KMT2AMEN1LMNAHTT
SCHEMBL702317 0.69 NPSR1 (0.45) CNR2FAAHKMT2AMEN1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124026-B2 Lateral flow diagnostic devices with instrument controlled fluidics EPOCAL INC. (CA) 2012-02-28 US disclosed
US-20100202926-A1 LATERAL FLOW DIAGNOSTIC DEVICES WITH INSTRUMENT CONTROLLED FLUIDICS EPOCAL INC. (CA) 2010-08-12 US disclosed
US-7722817-B2 Lateral flow diagnostic devices with instrument controlled fluidics EPOCAL INC. (CA) 2010-05-25 US disclosed
US-20050047972-A1 Instrument controlled integrated, one step analyte detection and testing; consistency, sensitivity; simplicity, low cost, speed SIEMENS HEALTHCARE DIAGNOSTICS INC. 2005-03-03 US disclosed