Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631526 | 0.91 | ROS1 (0.40) | PTGS2F10F2PRSS1PRSS2 | |
| SCHEMBL8628932 | 0.89 | ROS1 (0.41) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8631613 | 0.89 | PTGS2 (0.43) | PTGS2PTGS1F10ALDH1A1MAPT | |
| SCHEMBL8633944 | 0.86 | F10 (0.48) | F10F2 | |
| SCHEMBL8631834 | 0.85 | PTGS2 (0.46) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8629992 | 0.84 | PKM (0.48) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL7778030 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8634432 | 0.83 | PTGS2 (0.44) | PTGS2PTGS1F10F2PRSS1 | |
| SCHEMBL8635023 | 0.81 | FEN1 (0.44) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8627604 | 0.80 | PTGS2 (0.41) | PTGS2PTGS1F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |