Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818204 | 0.82 | SLC9A1 (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL1116597 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28789747 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30646221 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2365661 | 0.79 | METAP2 (0.43) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL2791036 | 0.77 | METAP2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3684019 | 0.77 | METAP2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3682415 | 0.77 | METAP2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3680794 | 0.77 | METAP2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3689576 | 0.77 | METAP2 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668855-B1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS FOR USE AS CHELATING AGENTS | AMERSHAM INT PLC (GB) | 1998-06-24 | — | — | EP | disclosed |