Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624551 | 0.92 | TRPV1 (0.51) | TRPV1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL8627064 | 0.87 | EPHX1 (0.50) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL8042523 | 0.85 | NPSR1 (0.51) | TRPV1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL8629884 | 0.85 | EPHX1 (0.52) | MAPTNPC1MEN1KMT2ALMNA | |
| SCHEMBL8626596 | 0.82 | MEN1 (0.54) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8626573 | 0.80 | RAF1 (0.49) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8625640 | 0.78 | MAPT (0.46) | MAPTNPC1MEN1KMT2ALMNA | |
| SCHEMBL8625695 | 0.77 | NPC1 (0.47) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8307879 | 0.72 | ABCB11 (0.47) | TRPV1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL8624699 | 0.71 | FPR2 (0.51) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |