Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629884 | 0.95 | EPHX1 (0.52) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL8626596 | 0.94 | MEN1 (0.54) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL8626573 | 0.90 | RAF1 (0.49) | MEN1KMT2ANPC1HTTMAPT | |
| SCHEMBL8628166 | 0.87 | TRPV1 (0.52) | MEN1KMT2ANPC1LMNAHTT | |
| SCHEMBL8625640 | 0.87 | MAPT (0.46) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL8625695 | 0.86 | NPC1 (0.47) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL8307879 | 0.80 | ABCB11 (0.47) | KMT2ALMNAHTTMAPTPOLB | |
| SCHEMBL8624699 | 0.80 | FPR2 (0.51) | MEN1KMT2ANPC1LMNAHTT | |
| SCHEMBL8443181 | 0.78 | CCR2 (0.47) | KMT2ALMNAMAPTPOLBMCL1 | |
| SCHEMBL8624551 | 0.77 | TRPV1 (0.51) | MEN1KMT2ANPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |