Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 6/20 | 0.41 |
| ▸ | EDNRA | P25101 | 6/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448711 | 0.88 | HPGDS (0.47) | HPGDSLTA4HESR2PDE3BPDE3A | |
| SCHEMBL18930006 | 0.80 | NPC1 (0.46) | HPGDSLTA4HCCNCCDK8IL2 | |
| SCHEMBL942521 | 0.78 | HPGDS (0.47) | HPGDSLTA4HEDNRBEDNRAIMPDH2 | |
| SCHEMBL7129733 | 0.78 | HPGDS (0.50) | HPGDSLTA4HIMPDH2HDAC4HPGD | |
| SCHEMBL5027378 | 0.77 | IL2 (0.44) | HPGDSLTA4HEDNRBEDNRAIMPDH2 | |
| SCHEMBL5571760 | 0.77 | LTA4H (0.70) | HPGDSLTA4HEDNRBEDNRAHDAC4 | |
| SCHEMBL301469 | 0.77 | HPGDS (0.71) | HPGDSLTA4HEDNRBEDNRAHDAC4 | |
| SCHEMBL2152660 | 0.76 | HPGDS (0.61) | HPGDSLTA4HHDAC4 | |
| Toluene SCHEMBL28904988 | 0.76 | HPGDS (0.61) | HPGDSLTA4HEDNRBEDNRAHDAC4 | |
| SCHEMBL16159830 | 0.76 | LTA4H (0.59) | HPGDSLTA4HENPP3ENPP1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716855-A | WITH TWO ENCAPSULATED HYDROPHOBIC CHROMOGENS SELECTED SO THAT THE EMISSIONS OF ONE (WHEN EXPOSED TO LIGHT) WILL ACTIVATE THE OTHER, FOR BIOLOGICAL MARKERS | SOCIETE PROLABO (FR) | 1998-02-10 | — | — | US | disclosed |