SCHEMBL862850

SCHEMBL862850

CS(=O)(=O)OCCCC(=O)c1ccc(OC2CCCCO2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HRH3 Q9Y5N1 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
STS P08842 5/20 0.37
NPC1 O15118 1/20 0.36
HRH2 P25021 1/20 0.36
HRH1 P35367 1/20 0.36
PDE4B Q07343 1/20 0.36
HSD11B1 P28845 1/20 0.36
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862848 0.84 KMT2A (0.49) MEN1KMT2AL3MBTL1STSNPC1
SCHEMBL862849 0.83 MEN1 (0.50) MEN1KMT2AHRH3L3MBTL1NPC1
SCHEMBL863077 0.82 MEN1 (0.52) MEN1KMT2AHRH3L3MBTL1NPC1
SCHEMBL6210554 0.77 MEN1 (0.51) MEN1KMT2AHRH3L3MBTL1NPC1
SCHEMBL863094 0.77 DHFR (0.39) MEN1KMT2ANPC1HSD11B1
SCHEMBL5722254 0.76 MEN1 (0.50) MEN1KMT2AHRH3NPC1PDE4B
SCHEMBL24041849 0.76 MEN1 (0.43) MEN1KMT2ANPC1
SCHEMBL9860211 0.75 MEN1 (0.49) MEN1KMT2AHRH3STSNPC1
SCHEMBL2281345 0.74 SMN1; SMN2 (0.60) MEN1KMT2AHRH3L3MBTL1NPC1
SCHEMBL1186911 0.74 MEN1 (0.52) MEN1KMT2ANPC1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME ALK, AOX1, OGFR MEN1 4097/4885KMT2A 1543/4885HRH3 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.