Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631430 | 0.87 | S1PR1 (0.42) | KDM4ES1PR1MAPK1TDP1NR1H2 | |
| SCHEMBL8632573 | 0.85 | KDM4E (0.39) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL8629892 | 0.81 | KDM4E (0.44) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL8628573 | 0.80 | MAPT (0.43) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL9157997 | 0.79 | S100B (0.44) | KDM4ES1PR1SLC16A3SLC16A1NR1H2 | |
| SCHEMBL6123766 | 0.76 | S100B (0.50) | KDM4ES1PR1MAPK1TDP1MEN1 | |
| SCHEMBL8633500 | 0.76 | CNR2 (0.47) | KDM4EMAPK1TDP1MEN1KMT2A | |
| SCHEMBL9095190 | 0.74 | S1PR1 (0.43) | KDM4ES1PR1SLC16A3SLC16A1ALDH1A1 | |
| SCHEMBL18831064 | 0.74 | S1PR1 (0.43) | S1PR1MAPK1ACHEMEN1KMT2A | |
| SCHEMBL8632565 | 0.71 | MAPT (0.39) | MEN1KMT2AALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |