Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632573 | 0.87 | KDM4E (0.39) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL9015952 | 0.86 | KDM4E (0.48) | MAPTPOLBKDM4EMAPK1ALDH1A1 | |
| SCHEMBL1059031 | 0.86 | MAPT (0.46) | MAPTMEN1KMT2APOLBCNR2 | |
| SCHEMBL8629892 | 0.85 | KDM4E (0.44) | MEN1KMT2APOLBCNR2KDM4E | |
| SCHEMBL11674868 | 0.82 | CNR2 (0.46) | MEN1KMT2APOLBNPSR1CNR2 | |
| SCHEMBL8628545 | 0.80 | KDM4E (0.36) | MEN1KMT2APOLBKDM4EMAPK1 | |
| SCHEMBL8633500 | 0.80 | CNR2 (0.47) | MEN1KMT2APOLBCNR2KDM4E | |
| SCHEMBL11676001 | 0.78 | CNR2 (0.42) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL22042269 | 0.76 | KDM4E (0.34) | KDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL107013 | 0.76 | CNR2 (0.49) | MAPTMEN1KMT2APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |