Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | NRP1 | O14786 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631602 | 0.91 | CDC25A (0.43) | PRMT1KDM1AEDNRBEDNRACDC25A | |
| SCHEMBL8634744 | 0.90 | GAA (0.44) | NRP1ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL8629951 | 0.87 | MAPT (0.43) | KDM1AEDNRBEDNRACDC25ACDC25B | |
| SCHEMBL8629350 | 0.87 | SMN1; SMN2 (0.46) | KDM1AEDNRBEDNRAALDH1A1GAA | |
| SCHEMBL8630563 | 0.85 | PRMT1 (0.43) | PRMT1KDM1AALDH1A1GAATP53 | |
| SCHEMBL8633160 | 0.84 | MEN1 (0.43) | KDM1AEDNRBEDNRACDC25ACDC25B | |
| SCHEMBL8631666 | 0.83 | EDNRB (0.42) | PRMT1KDM1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8627773 | 0.83 | PRMT1 (0.42) | PRMT1KDM1AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8635042 | 0.82 | PDE9A (0.43) | CDC25ACDC25BALDH1A1GAAMAPT | |
| SCHEMBL8634716 | 0.81 | PI4KB (0.42) | KDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |