Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628573 | 0.86 | MAPT (0.43) | KDM4EL3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL9371410 | 0.85 | KDM4E (0.59) | KDM4EL3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL1059031 | 0.84 | MAPT (0.46) | MAPTALDH1A1TSHRLMNAPOLB | |
| SCHEMBL144082 | 0.81 | ALDH1A1 (0.37) | KDM4EL3MBTL1MAPTALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9015914 | 0.80 | ALDH1A1 (0.36) | KDM4EL3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL10771235 | 0.79 | KDM4E (0.49) | KDM4EL3MBTL1MAPTALDH1A1TSHR | |
| SCHEMBL11694085 | 0.78 | ALDH1A1 (0.41) | KDM4EL3MBTL1ALDH1A1GAALMNA | |
| SCHEMBL17199803 | 0.78 | KDM4E (0.44) | KDM4EL3MBTL1GAAAPOBEC3G | |
| SCHEMBL19158147 | 0.77 | MAPT (0.49) | KDM4EL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL8635706 | 0.74 | MAPT (0.40) | MAPTALDH1A1TSHRMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |