SCHEMBL8628607

SCHEMBL8628607

CC(=O)N1CCN(C(=O)Cl)C1=O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
NOTUM Q6P988 12/20 0.33
MAPK1 P28482 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4335919 0.88 NOTUM (0.39) BRD4NOTUMMAPK1CYP2D6CYP2C9
SCHEMBL11826368 0.88 LMNA (0.30)
SCHEMBL11291689 0.77 CNR2 (0.33) BRD4
SCHEMBL11733469 0.77
SCHEMBL11597603 0.77 CYP1A2 (0.36) CYP2C9
SCHEMBL11731843 0.77 POLB (0.41)
SCHEMBL11735338 0.77 KMT2A (0.36)
SCHEMBL11728865 0.77 ALDH1A1 (0.33)
SCHEMBL11593861 0.77 KMT2A (0.35)
SCHEMBL8271343 0.74 MAPK1 (0.38) BRD4NOTUMMAPK1CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1446802-A Chemosynthesis method of 1-chloroformyl-3-acetyl-2-imidazolidinone UNIV ZHEJIANG POLYTECHNIC (CN) 2003-10-08 CN claimed
CN-119504593-A Production process of high-purity 2-imidazolone 烟台中科荣达新材料有限公司 2025-02-25 CN disclosed
CN-1951801-A Process for preparing high purity hydrochloric acid by circularly absorbing hydrogen chloride by-product UNIV ZHEJIANG TECHNOLOGY (CN) 2007-04-25 CN disclosed
CN-1446802-A Chemosynthesis method of 1-chloroformyl-3-acetyl-2-imidazolidinone UNIV ZHEJIANG POLYTECHNIC (CN) 2003-10-08 CN disclosed
CN-1446802-A Chemosynthesis method of 1-chloroformyl-3-acetyl-2-imidazolidinone UNIV ZHEJIANG POLYTECHNIC (CN) 2003-10-08 CN disclosed
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
US-5089490-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4758556-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 US disclosed
EP-0048165-A1 Bis-tetrazolemethyl substituted beta-lactam antibiotics, their preparation and pharmaceutical formulations containing them ELI LILLY AND COMPANY (US) 1982-03-24 EP disclosed
US-4093722-A ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DT) 1978-06-06 US disclosed
US-4086340-A ANTIBIOTIC; ANIMAL GROWTH PROMOTER BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed
US-4009272-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed
US-3983105-A Penicillins BAYER AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed
US-3978056-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3975375-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed
US-3974142-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3974141-A IMIDAZOLIDINYL-CARBAMIDOBACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3972869-A Penicillins BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3972870-A IMIDAZOLIDINYL-CARBAMIDO-BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed