SCHEMBL8628683

SCHEMBL8628683

CC(Cc1ccc(O)cc1)C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.47
ESR2 Q92731 4/20 0.47
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
TAAR1 Q96RJ0 3/20 0.46
SLC6A2 P23975 1/20 0.46
LY96 Q9Y6Y9 1/20 0.45
SLC7A5 Q01650 1/20 0.42
MIF P14174 1/20 0.41
ITGA4 P13612 1/20 0.41
ITGB7 P26010 1/20 0.41
BLM P54132 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.39
MDM4 O15151 1/20 0.39
MDM2 Q00987 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15697338 1.00 ESR1 (0.47) ESR1ESR2CTSSCTSKTAAR1
SCHEMBL12317087 0.85 CYP3A4 (0.42) SLC7A5ITGA4ITGB7
SCHEMBL21601599 0.85 ITGA4 (0.51) CTSSCTSKITGA4ITGB7TSHR
SCHEMBL12029131 0.85 ITGA4 (0.51) CTSSCTSKITGA4ITGB7TSHR
SCHEMBL13108100 0.85 ITGA4 (0.51) CTSSCTSKITGA4ITGB7TSHR
SCHEMBL23582645 0.84 KMT2A (0.45) ITGA4ITGB7KMT2A
SCHEMBL2723926 0.84 LDHA (0.54) ITGA4ITGB7
SCHEMBL13108101 0.84 ACACB (0.51) CTSK
SCHEMBL4025857 0.83 ESR1 (0.47) ESR1ESR2CTSSCTSKTAAR1
SCHEMBL630703 0.82 SLC7A5 (0.57) ESR1ESR2CTSSCTSKTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997045884-A9 FLAME-RETARDANT BATTERY CASING 1998-03-12 WO disclosed
EP-0595832-A1 HIGH MODULUS TOUGHENED POLYAMIDE COMPOSITION. EXXON CHEMICAL PATENTS INC (US) 1994-05-11 EP disclosed
WO-1992021722-A1 HIGH MODULUS TOUGHENED POLYAMIDE COMPOSITION EXXON CHEMICAL PATENTS INC. (US) 1992-12-10 WO disclosed
US-5047476-A Mixing copolymer containing hydrolyzable grafted silicon group dihydrocarbyltin oxide, carboxylic acid, water, then heating UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1991-09-10 US disclosed