Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8628727 | 1.00 | MEN1 (0.32) | MEN1LMNAHPGDALOX15ALOX12 | |
| SCHEMBL8625850 | 0.87 | HPGD (0.32) | HPGDSMN1; SMN2 | |
| SCHEMBL8631720 | 0.87 | ERN1 (0.33) | ERN1 | |
| SCHEMBL8625853 | 0.87 | HPGD (0.32) | HPGDSMN1; SMN2 | |
| SCHEMBL8631716 | 0.87 | ERN1 (0.33) | ERN1 | |
| SCHEMBL8628729 | 0.83 | ERN1 (0.33) | MEN1LMNAHPGDALOX15ALOX12 | |
| SCHEMBL8625247 | 0.75 | LMNA (0.33) | LMNAHTT | |
| SCHEMBL8631726 | 0.75 | ERN1 (0.35) | ALOX12HTTERN1 | |
| SCHEMBL8629068 | 0.74 | ADRA1D (0.34) | MEN1LMNAHPGDHTTKMT2A | |
| SCHEMBL8629066 | 0.74 | ADRA1D (0.34) | MEN1LMNAHPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705243-B1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE POULENC AGROCHIMIE (FR) | 1998-06-24 | — | — | EP | disclosed |
| US-5684206-A | CONDENSING METHYL ORGANO KETONE WITH A BENZONITRILE IN PRESENCE OF STRONG BASE | RHONE-POULENC ARGOCHIMIE (FR) | 1997-11-04 | — | — | US | disclosed |