Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631726 | 0.86 | ERN1 (0.35) | ERN1ALOX12HTT | |
| SCHEMBL8625856 | 0.86 | SLC6A4 (0.43) | MEN1HPGDKMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL8628725 | 0.83 | MEN1 (0.32) | ERN1MEN1LMNAHPGDALOX15 | |
| SCHEMBL8628727 | 0.83 | MEN1 (0.32) | ERN1MEN1LMNAHPGDALOX15 | |
| SCHEMBL8629071 | 0.76 | ALDH1A1 (0.42) | MEN1LMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8632344 | 0.76 | DGAT1 (0.38) | MEN1HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8631720 | 0.75 | ERN1 (0.33) | ERN1 | |
| SCHEMBL8631716 | 0.75 | ERN1 (0.33) | ERN1 | |
| SCHEMBL18786842 | 0.74 | ERN1 (0.43) | ERN1KMT2A | |
| SCHEMBL8625853 | 0.72 | HPGD (0.32) | HPGDSMN1; SMN2SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705243-B1 | BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES | RHONE POULENC AGROCHIMIE (FR) | 1998-06-24 | — | — | EP | disclosed |
| US-5684206-A | CONDENSING METHYL ORGANO KETONE WITH A BENZONITRILE IN PRESENCE OF STRONG BASE | RHONE-POULENC ARGOCHIMIE (FR) | 1997-11-04 | — | — | US | disclosed |