Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | UBE2I | P63279 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629750 | 0.89 | MAPT (0.46) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8631761 | 0.89 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL8631337 | 0.88 | PTGS2 (0.50) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8630525 | 0.87 | CCR4 (0.41) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8631550 | 0.87 | PTGS2 (0.58) | PTGS2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8627799 | 0.86 | PTGS2 (0.49) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8632376 | 0.85 | MAPT (0.38) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8632158 | 0.85 | MAPT (0.38) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8633047 | 0.85 | MAPT (0.40) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8631961 | 0.85 | PTGS2 (0.38) | PTGS2MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |