Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.38 |
| ▸ | FEN1 | P39748 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631765 | 0.88 | PTGS2 (0.45) | F10F2PTGS1PTGS2 | |
| SCHEMBL8631340 | 0.88 | PTGS2 (0.37) | F10F2PTGS1PTGS2TRPV1 | |
| SCHEMBL8631554 | 0.88 | PTGS2 (0.46) | F10ALOX5APFEN1F2PTGS1 | |
| SCHEMBL8627803 | 0.86 | PTGS2 (0.37) | F10F2PRSS1PTGS1PTGS2 | |
| SCHEMBL8631853 | 0.85 | ALOX5AP (0.40) | F10ALOX5APFEN1F2KLKB1 | |
| SCHEMBL8631100 | 0.85 | PTGS2 (0.39) | F10F2PTGS1PTGS2TRPV1 | |
| SCHEMBL7779636 | 0.85 | PTGS2 (0.50) | PTGS1PTGS2 | |
| SCHEMBL8629763 | 0.85 | F10 (0.39) | F10F2PRSS1PTGS1PTGS2 | |
| SCHEMBL8635118 | 0.83 | F10 (0.46) | F10F2PTGS1PTGS2 | |
| SCHEMBL8634395 | 0.83 | PTGS2 (0.38) | F10F2PRSS1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |