Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | BPTF | Q12830 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889112 | 0.89 | HTT (0.51) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL19448909 | 0.84 | TSHR (0.47) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL19436450 | 0.83 | MAPT (0.50) | TSHRHTTAPOBEC3AAPOBEC3GMAPK1 | |
| SCHEMBL14045969 | 0.81 | ALDH1A1 (0.66) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL987150 | 0.81 | LMNA (0.45) | TSHRHTTLMNACYP1A2CYP3A4 | |
| SCHEMBL502534 | 0.81 | PKM (0.67) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL1004561 | 0.81 | TSHR (0.59) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL12526814 | 0.81 | LMNA (0.67) | TSHRHTTLMNACYP1A2CYP3A4 | |
| SCHEMBL11850840 | 0.81 | TSHR (0.59) | TSHRHTTAPOBEC3AAPOBEC3GBPTF | |
| SCHEMBL11594251 | 0.81 | CA12 (0.67) | TSHRHTTMAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756691-A | YELLOW | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |